Northwich Victoria manager Andy Mutch resigned on Saturday within minutes of his side's 1-2 home defeat to Belper Town.
The Evo-Stik NPL First Division South manager saw two of his players red carded during the defeat at Marston Road.
Mutch's assistant Adriano Rigoglioso has also left the Vics who say a club statement will be issued in due course on replacing the pair.
Northwich Victoria currently lay eighth in the table and 21 points behind leaders Coalville Town.
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